Engenharia Biomédica
URI Permanente para esta coleção
Navegar
Submissões Recentes
Item Efeitos da terapia ILIB modificada em pacientes com sepse internados no ambiente hospitalar(ILIB, 2024) Sousa, Adriano Correia de; Andrade, Ana Laura Martins deIntroduction: sepsis is a systemic inflammatory response syndrome (SIRS) triggered by a suspected or confirmed infection, which can progress to severe sepsis when associated with organ dysfunction or septic shock. This condition is one of the main challenges for healthcare organizations, being one of the main causes of death in hospitalized patients. Objective: to evaluate the effects of modified ILIB therapy in patients with sepsis admitted to a hospital setting. Methodology: Thirty septic patients participated in the study and were randomly divided into two groups: control group (CG, n = 15), in which participants received the ILIB technique (modified) with the laser turned off, and treated group (GILIB, n = 15), which received the ILIB technique with the laser turned on, both for 30 minutes daily for five consecutive days. Conventional treatments were maintained in both groups. Clinical parameters, such as leukocytes, PaCO2, PaO2, lactate, creatinine, SpO2, pH and HCO3, were monitored daily. Results: modified ILIB therapy provided significant improvements in the clinical parameters of patients treated in the ILIB group, leukocytes (p<0.001), ph (p<0.001), PaO2 (p<0.05), PaCO2 presented an average within normal levels, HCO3 there were no significant differences, lactate on the 4th and 5th (p<0.05), SpO2 on the 2nd day (p<0.001), 3rd (p<0.0001), 4th (p<0.05), 5th (p<0.0001) and Creatinine on the 1st day of intervention (p<0.0001), 2nd (p<0.05), 3rd (p<0.05), 4th (p<0.05) and 5th (p<0.05). Conclusion: These improvements suggest that the modified ILIB may be a promising therapeutic option in the management of sepsis, contributing to patient recovery.Item Influência da Terapia por Fotobiomodulação no tratamento de condições inflamatórias pulmonares e seu impacto sobre o Covid-19(Universidade Brasil, 2021) Macedo, Daniela Bezerra; Tim, Carla Roberta; Garcia, Lívia AssisToday we are facing a pandemic that continually causes high rates of deaths and catastrophic and countless economic and psychosocial consequences. Thus, this period requires a rapid search for viable procedures that can allow us to use safe and noninvasive clinical tools as prophylactic or even adjuvant methods in the treatment of COVID-19, thus constituting an important challenge to the medical clinic. Evidence shows that photobiomodulation therapy (PBMT) is shown to attenuate the inflammatory process and reduce respiratory disorders similar to acute lung injury (ALI), complications associated with infections, such as that caused by the new Coronavirus (SARS-CoV-2). Thus, the aim of this study was to evaluate the influence of laser PBMT on infrared length in the treatment of ALI, one of the main critical complications of COVID-19 infection, in an experimental model of rats. Twenty-four male Wistar rats were randomly allocated into three experimental groups (n = 8): Control (CG); LPA (LPA); LASER-treated LPA (LPAL). For the treatment, a laser equipment (808 nm; 30 mw; 1.8 J) was applied at three points (anterior region of the trachea and in the venereal regions of the thorax bilaterally) in the period of 1 and 24 hours after lpa induction. Descriptive histopathological analysis, lung injury score, analysis of the number of inflammatory cells, interleukin 1 β (IL-1β) and interleukin 10 levels (IL-10) were performed for treatment evaluation. In the results, it was possible to observe that the treatment reduced inflammatory infiltrates, there was thickening of the alveolar septum and the pulmonary injury score when compared to the LPA group. In addition, laser PBMT showed lower immunoexpression of IL-1β, however, it did not alter the levels of pulmonary IL-10. Thus, it can be concluded with this experimental study that infrared laser PBMT was efficient in attenuating ALI, one of the main complications of COVID-19, since it was able to reduce the inflammatory process, as well as increase the production of anti-inflammatory cytokines.Item Utilização do aplicativo ECG do Apple Watch para medida do intervalo RR do eletrocardiograma(Universidade Brasil, 2021) Barreto, Patric Roberto Ferreira; Marciano, Fernanda RobertaRoutine laboratory tests depend on the quantitative analysis of various biomarkers and biochemical parameters in biological samples, in view of this there is a growing search for biosensors and systems in the form of wearable technologies for use in the healthcare field, given the scarcity of resources and the widespread use of 12-lead electrocardiogram (ECG) substitutes, some studies show a good agreement between the measurement of ECG measured on a smart watch and a 12-lead ECG, therefore the use of these technologies is promising as health assessment and monitoring devices. The work had the general objective analyzing the correlation of the RR intervals of the ECG obtained by the conventional method and by the Apple Watch's ECG, measuring the RR intervals identified between two QRS complexes selected in the ECG records, identifying the presence of P waves followed by QRS complex and finally classifying cardiac rhythms. It was a randomized, cross-sectional study with a quantitative approach, 20 individuals were selected and invited to participate in this research, who were approached after a medical consultation with the cardiologist and to enter the evaluation process they had to have the following inclusion criteria, these being: healthy, male, aged 20 to 40 years old, no diagnosis of asthma, interstitial lung disease and cardiovascular or cardiomyopathic impairment, they cannot be using any type of drugs, all were distributed in only 1 simple random sampling group, Group 1, which study participants were submitted to the 12-lead ECG exam and immediately after 30 seconds (s) to the use of the Apple Watch Series 4, to perform the ECG performed by the brand's own app, the two exams were performed with the participants lying in the supine position. After applying Pearson's correlation coefficient, a positive and strong correlation was found, it was also possible to verify the presence of P waves followed by the QRS complex indicating a conclusion of sinus rhythm. Therefore, it was possible to verify the correlation between the R-R intervals and the identification of sinus rhythm by the Apple Watch.