Mestrado
URI permanente desta comunidadehttps://repositorioacademico.universidadebrasil.edu.br/handle/123456789/30
Navegar
2 resultados
Resultados da Pesquisa
Item Efeitos da Fotobiomodulação no processo de cicatrização da lesão por pressão(Universidade Brasil, 2022) Oliveira, Laricy Rodrigues de; Baptista, AlessandraCurrently, the prevention and treatment of Pressure Ulcer (PU) is the focus of multidisciplinary actions in different health care settings. Photobiomodulation is a form of phototherapy proposed in the treatment of PU, as it is able to modulate the quality and speed of the healing process. The objective of this study was to evaluate the quality of life (QoL) of the individual affected by PU, as well as to evaluate the modulation of the PU healing process, through photobiomodulation. This is a qualitative-quantitative clinical study, in which 10 volunteers with PU participated, treated at home. Participants were randomly divided into two groups, according to the therapeutic intervention: Control Group (n=5); treated with calcium and sodium alginate coating and Photobiomodulation Group (n=5); treated with photobiomodulation, where the PUs received punctual irradiation, 4J/point, on alternate days, with a low power laser emitting at 660 nm, with 100 mW of power, for 40 s. All volunteers in this study received treatment for 4 weeks. Participants QoL was analyzed using the WHOQOL-BREF questionnaire, before and after the interventions. The PU healing process was evaluated by the PUSH instrument, on the 1st, 15th and 29th days. The PUs were photographed in a standardized way, on the respective days, to compare the evolution of the repair process. For data analysis, the Shapiro Wilk normality test and the two way ANOVA test of variance were applied, and the means were compared using the Tukey test with a significance of 5%, being considered statistically different when p<0.05. The perception of QoL in the Photobiomodulation Group was regular in the initial phase of treatment, evolving to very good in the final phase, while the volunteers in the Control Group maintained a very good response from the beginning to the end of the treatment. The evaluation using the PUSH instrument showed a gradual temporal improvement in the PU repair process, regardless of the treated group. The comparison of photographic images revealed that there was a reduction in the staging of PUs in both groups. Therefore, we can conclude that photobiomodulation, in the parameters tested in this study, can be a good alternative in relation to QoL and modulation of the PU healing process.Item Influência da Terapia por Fotobiomodulação no tratamento de condições inflamatórias pulmonares e seu impacto sobre o Covid-19(Universidade Brasil, 2021) Macedo, Daniela Bezerra; Tim, Carla Roberta; Garcia, Lívia AssisToday we are facing a pandemic that continually causes high rates of deaths and catastrophic and countless economic and psychosocial consequences. Thus, this period requires a rapid search for viable procedures that can allow us to use safe and noninvasive clinical tools as prophylactic or even adjuvant methods in the treatment of COVID-19, thus constituting an important challenge to the medical clinic. Evidence shows that photobiomodulation therapy (PBMT) is shown to attenuate the inflammatory process and reduce respiratory disorders similar to acute lung injury (ALI), complications associated with infections, such as that caused by the new Coronavirus (SARS-CoV-2). Thus, the aim of this study was to evaluate the influence of laser PBMT on infrared length in the treatment of ALI, one of the main critical complications of COVID-19 infection, in an experimental model of rats. Twenty-four male Wistar rats were randomly allocated into three experimental groups (n = 8): Control (CG); LPA (LPA); LASER-treated LPA (LPAL). For the treatment, a laser equipment (808 nm; 30 mw; 1.8 J) was applied at three points (anterior region of the trachea and in the venereal regions of the thorax bilaterally) in the period of 1 and 24 hours after lpa induction. Descriptive histopathological analysis, lung injury score, analysis of the number of inflammatory cells, interleukin 1 β (IL-1β) and interleukin 10 levels (IL-10) were performed for treatment evaluation. In the results, it was possible to observe that the treatment reduced inflammatory infiltrates, there was thickening of the alveolar septum and the pulmonary injury score when compared to the LPA group. In addition, laser PBMT showed lower immunoexpression of IL-1β, however, it did not alter the levels of pulmonary IL-10. Thus, it can be concluded with this experimental study that infrared laser PBMT was efficient in attenuating ALI, one of the main complications of COVID-19, since it was able to reduce the inflammatory process, as well as increase the production of anti-inflammatory cytokines.