Aplicação da Espectroscopia Raman Confocal para rastreamento de um produto cosmético pela unha humana no tratamento da síndrome de unhas frágeis

Abstract

Fragile nail syndrome has a high prevalence in medical offices and adherence to treatment with fortifying products is still a challenge, since, in Brazilian culture, there is a custom of fading nails weekly. In this context, the present work aims to apply Confocal Raman Spectroscopy to determine the ability of a nail-strengthening product to permeate through enamel with one and two layers and reach the nail, allowing the treatment of syndrome of fragile nails on enameled nails. For this, 05 (five)participants were selected, between men and women, aged 19 to 55 years. The permeation of the product was measured in virgin nail, with one and two layers of enamel. The product was deposited after one hour of enamel application and permeation was measured after one hour of product deposition. It was observed that the product permeates enamel and penetrates the nail up to approximately 18 μm. It was also possible to detect the presence of the main components of this product at approximately 18 μm depth in the nail. Therefore, the product crosses the enamel layer and permeates the nail facilitating the treatment in enameled nails. This result becomes promising because it provides for greater adherence of patients with pathology to treatment. The permeation in virgin nail is shown five times higher than the enameled nail with one and two layers, which proves a good permeation of the product. In this way, Raman Confocal Spectroscopy will bring subsidies to the cosmetic industry for sustaining the ability of a product to permeate the enamel layer and treat the nail.