Efeito de óleos essenciais in natura e ozonizados sobre o desenvolvimento de fungos patogênicos
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Data
2020
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Universidade Brasil
Resumo
Some species of fungi are capable of causing mycotic infections. One of these
infections is dermatophytosis, caused by a group of fungi, called dermatophytes.
another infection is sporotrichosis, caused by species of Prothorax schenckii. The
treatment of the disease is carried out using conventional antifungals. The emergence
of resistant strains has led to alternative treatments, such as natural medicines or the
use of ozone gas. The objective of this research was to evaluate the antifungal activity
of fresh and ozonated essential oils against Trichophyton mentagrophytes,
Trichophyton rubrum, and Sporothrix schenckii. In natura and ozonized essential oils
of Cinnamomum cassia, Eugenia Caryphollata, Cymbopogon winterianus, Eucalyptus
globulus, Eucalyptus staigeriana and Mentha piperita were used, evaluated for
antifungal activity against the microorganism lineage. The oils were ozonized in corona
equipment. The microdilution technique was used to assess the minimum inhibitory
concentration (MIC) and the minimum fungicidal concentration (MFC). The fungicidal
kinetics of essential oils were determined. The data obtained were evaluated by the
Mann-Whitney test and by the east of Kruskal-Wallis. The fungus T. mentagrophytes
was more resistant. T. rubrum showed less resistance to treatments, showing
decreases in microbial count in the first moments of exposure. The Spothrix fungus
showed greater resistance to cinnamon, clove and Eucalyptus staigeriana oils,
showing a decrease in microbial count variation. In general, the results show the
possibility of use in antifungal therapy against the studied microorganisms.
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Palavras-chave
Trichophyton mentagrophytes, Trichophyton rubrum, Sporothrix schenckii, Ozônio, Plantas medicinais