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Aparelhos autoligados : indicação e comparação com o sistema convencional
(Universidade Brasil, 2022) Santos, Beatriz Magri dos; Rolim, Valéria Cristina Lopes Barros; Gimenez, Carla Maria Melleiro
Avaliação do efeito do extrato aquoso da casca do caule de “Ximenia Americana L.” incorporado à hidrogel à base de gelatina metacrilato (gelma) no processo de reparo ósseo induzido em ratos
(Universidade Brasil, 2023) Leal, Seânia Santos; Costa, Adriana Pavinatto da; Oliveira, Rauirys Alencar de
Several physiotherapeutic modalities have been studied with the aim of promoting bone repair. In the biomedical context, the use of Biomaterials has been studied to stimulate this process. The present work aims to produce, characterize and evaluate the effect of the stem bark extract of “Ximenia americana L.” incorporated into gelatin methacrylate hydrogel (GelMA) associated or not with photobiomodulation (LED) therapy in the bone repair process induced in rats. To this end, the materials GelMA and GelMA + stem bark extract of “Ximenia americana L.” that were used in in vivo experiments. Animal tests were carried out using 50 male Wistar rats distributed into 5 distinct groups called: control group (CG), GelMA group (GG), Gelma + LED group (GLED), GelMA group + Ximenia americana extract ( GE) and GelMA + Ximenia americana extract _ LED (GELED) group, which were subjected to the induced fracture protocol in the diaphyseal region of the right tibia and treated with light by emission diode 858 nm and energy dose 6J in an established period of 15 and 30 days, being euthanized throughout the same cycle. To verify the effects of the therapies, histological analyzes and Raman spectroscopy were carried out. The results showed that 15 days after inducing injury in the tibia of rats, in the GE group, bone neoformation was higher than in the control group and between the GG and GE groups. In 30 days of the experiment, there was also a difference in bone neoformation between the GELED group and the control group between the GE and control group. There was also a difference between the GG and GE and GELED groups. Given the results, it can be stated that the stem extract of “Ximenia americana L” incorporated into GelMA associated with photobiomodulation from LED is a potentiator of bone repair in an animal model.
Expansão esquelética palatina com dispositivo ortodôntico tipo MARPE
(Universidade Brasil, 2022) Arantes, Gabrieli de Magalhães; Rolim, Valéria Cristina Lopes Barros; Gimenez, Carla Maria Melleiro
Fotobiomodulação no tratamento de lesões por pressão: revisão sistemática com metanálise
(Universidade Brasil, 2021) Macedo, Suellen Pereira Rodrigues; Navarro, Ricardo Scarparo
Pressure sores (PS) are important causes of morbidity, especially in patients admitted to intensive care units. Besides having a high cost to the health system, it adds an additional risk for the patients because it imposes the loss of the skin constitutional barrier. Photobiomodulation (PBM) with low-level laser has been shown to be effective in the treatment of PS in different stages. There is no consensus on the protocols of irradiation parameters, wavelength, energy, dose, intervals between sessions. The objective of this study was to evaluate the effects of photobiomodulation in the treatment of pressure sores from a systematic review of literature and meta-analysis. This is a systematic review carried out according to the PRISMA guidelines, which included studies without restrictions on year and language of publication, published until January 2020. Randomized studies that compared the effects of low-level laser therapy with a control group in patients with pressure ulcers were included. The studies were analyzed, reported descriptively and combined in a meta-analysis, the heterogeneity of the studies was assessed and the combined Odds Ratio for total PS healing in the follow-up period and the combined mean percentage area reduction were calculated. Six randomized clinical trials were included in the qualitative analysis and five trials in the quantitative analysis. A total of 207 patients were randomized to either FBM or control. The studies reported PBM with low-level laser with different wavelengths within the therapeutic window, in the range of 600 nm (red), 800 nm and 900 nm (infrared). From these data, subgroup analysis was performed and the combined Odds Ratio for each band was calculated, and no statistically significant difference was found in the set of studies as a whole and in the subgroups (p> 0.05). Only two studies described the percentage of reduction of the PS area. Analysis of these combined data showed Odds Ratio values equal to 1.34 (95% CI 0.8 - 2.24; Z 1.11; p= 0.82) in favor of the PBM but without statistical significance (p> 0.05). Of the included studies, only PBM with low-level laser therapy using red laser (660 nm) promoted a significant difference in the reduction of PS (p< 0.05). It can be concluded that in the studies included, photobiomodulation with red low-level laser was effective in the healing process of pressure sores in stages 2 and 3. It is suggested to carry out other randomized clinical trials to analyze the parameters of photobiomodulation.
Nanocompósitos à base de hidroxiapatita e nanotubos de carbono como reforço em biopolimero heterólogo de fibrina derivado do veneno de serpente para regeneração óssea
(Universidade Brasil, 2021) Gouveia, Daniel Mussuri de; Kido, Hueliton Wilian; Cogo, José Carlos
Fibrin sealants (BHF), developed from human hematological derivatives, mimic physiological clots, being widely used in general, cosmetic and postoperative surgeries due to their hemostatic and adhesive action. BHF developed from the venom of Crotalus durissus terrificus (rattlesnake) is a heterologous thrombin-like derivative that converts fibrinogen into fibrin. As it is a natural product, in gel form, biodegradable, bioabsorbent, non-toxic and non-immunogenic. On the other hand, hydroxyapatite nanocomposites (nHAp) and carbon nanotubes (NTCs), produced by chemical synthesis assisted by the ultrasound technique, present bioactivity, are not cytotoxic and have a bactericidal effect. The aim of the present work is to evaluate the mixture of hydroxyapatite-based nanocomposites and carbon nanotubes with fibrin sealant as agents in the process of accelerating bone regeneration. The production of the nanocomposites consisted, firstly, in the synthesis of NTCs with multiple walls, followed by their functionalization to the O2 plasma and purification with an acid bath. With this material ready, the composite of nHAp with NTC was produced. Then, this material was added to the BHF and the physicochemical characterization of this mixture was carried out. The pellets formed by these mixtures were analyzed and photographed under scanning electron microscopy (SEM). These mixtures were also tested in MC3T3-E1 cell cultures to verify their toxicity. For this purpose, osteoblast cells were cultured and cell viability was verified using the alamarBlue® e LIVE/DEAD® Viability/Cytotoxicity technique. Experiments were also carried out in rats, inducing bone defect in tibias and verifying bone repair. All data were analyzed using the normality test, and the parametric results were submitted to the two-way ANOVA complemented by Tukey's post-test (p≤0,05). The results showed that there was a good homogeneous distribution of the mixtures and that the most suitable mixture for in vitro tests is that of BFH+nHAp and 1% and 2% carbon nanotubes. The mixture is not cytotoxic and promoted neoformation in the fracture area, demonstrating osteogenic potential in bone fractures.
Revisão bibliográfica de tratamento cirúrgico de persistência do ducto arterioso com o uso de hemoclip em cães
(Universidade Camilo Castelo Branco, 2018) Freitas, Alexandro da Silva; Oliveira, André Lacerda de Abreu
Revisão de literatura em Cisticercose Bovina
(Universidade Brasil, 2016) Souza, Camila Maraçati Jordão de; Falçoni, Fernanda Maria dos Santos de Morais
Bovine cysticercosis is another major zoonosis found in slaughterhouses , both because of its importance for public health and by its prevalence , determining economic losses, resulting in affected animals convictions, according to RIIPOA (Art.176) cysticercosis ("Cysticercus bovis”) - the carcasses will be sentenced with heavy infestations by "Cysticercus bovis" or when meat is watery or discolored.
Sarna demodécica
(Universidade Camilo Castelo Branco, 2016) Lopes, Karina de Souza; Martins, Juliana Dias
This research has as main objective to discuss the important aspects of demodectic mange. This work was carried out through literature searches made in books, internet, papers, theses, to guide the search. To achieve the objectives of the research, it was decided to descriptive and exploratory approach. The demodectic mange is a very common disease in the veterinary clinic, is caused by Demodex mite.The demodectic mange is a disease that inflames the skin of dogs and cats due to the amount of mites on the skin. All skin disease needs to be investigated and evaluated in detail, as well, will be able to discover the causes, symptoms, how to diagnose and how to treat. Many dogs had to be euthanized because of illness, because they could not cure nor control the disease. The pathology is confused with other skin diseases because of similar symptoms and skin infection. Currently, the gene is evaluated, the underlying disease and immunology, which aids in good recovery due to animal research. It is a common disease, but can have a severe state. Therefore, through the use of drugs considered as effective in the treatment of demodectic mange (amitraz, moxidectin and ivermectin), there is the possibility of 80% to 90% cure.
Sistema de vídeo extensômetro universal para simulação, previsão e indicação das propriedades mecânicas dos materiais
(Universidade Brasil, 2023) Carvalho, Antônio Carlos de; Rodrigues, Ione; Rodrigues, Ione; Costa, Mardoqueu Martins da; Rodrigues, Ione; Rodrigues
Utilização de palmilhas sensoriais para avaliação, percepção e correção do exercício em corredores iniciantes
(Universidade Brasil, 2021) Rocha, Gabriel Mauriz de Moura; Garcia, Lívia Assis; Almeida, Vilson Rosa de
The number of road runners has increased considerably all over the world. Analyzing variables such as plantar pressure and posture provide important information that helps to understand several factors related to running performance and prevent musculoskeletal injuries. The objective of this work was to evaluate, understand and correct the plantar pressure of beginner runners, through the proposal and application of training using sensory insoles and biofeedback. The present work was of field research type, with a longitudinal study with 30 participants. The experimental protocol was divided into three phases: in the first, the initial assessment of anthropometric data was carried out, assessment of the biomechanical characteristics of the foot, followed by static postural assessment using the Kinovea software and, subsequently, the assessment of static plantar pressure using the platform Pedana Sensor Medica with FreeStep® software; in the second phase, the participants performed the training protocol, for 4 weeks, totaling 12 treadmill running interventions and the use of the ARION® sensory insole with visual biofeedback, for 15 minutes in the first two weeks and 30 minutes in the last two. In the third phase, the same reassessment as in the first phase was carried out. Statistical analysis was performed with the SPSS Software for Windows version 20.0, considering the value of p ≤ 0.05. It was possible to demonstrate that there was a statistically significant variation between the measurements of plantar pressure in the forefoot after running training for the variables surface and surface/load ratio. In the investigation of the forefoot/rearfoot ratio, there was a significant difference for the surface, load and surface/load ratio variables. There was a statistical difference in the postural assessment after the protocol with a reduction in the angles of the head and lower limbs in the anterior view, the head on the left side in the lateral view and the left ankle and right lower limb in the posterior view. Experimental results demonstrated that the use of the sensory insole with biofeedback helps to improve the distribution of plantar pressure and postural angles of the participants. Therefore, it is possible to infer that the use of this device in new training methodologies, with a visual interface of the runner's biomechanical performance, can help reduce injuries and optimize the practice of road running.

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