Navegando por Autor "Nunez, Silvia Cristina"

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Aplicativo móvel multiplataformas para gestão de cuidados para idosos
(Universidade Brasil, 2021) Chagas, Renata Kelen; Nunez, Silvia Cristina
The aging of the world population has been taking place in recent decades as result of the decrease in birth rates and better health care that allows for an increase in life expectancy. Senile dementias are examples of diseases that can affect the elderly, reducing independence and self-care. With the presence of women in the labor market and the reduced number of children, the elderly must often live under the care of others who have professional experience to provide appropriate medical care, but lack of contact with the family and unfamiliarity with habits and tastes can reduce the quality of life of the elderly. Technological advances must be used to reduce the distance between families, caregivers, doctors and the elderly. The objective of this work is to develop an application for mobile devices that facilitates communication between health service providers for the elderly residing in long-stay institutions. The CuidaLife application was developed for a software operating system with input modules for registering elderly people, family members, doctors and caregivers. The developed application can be accessed through any smartphone, tablet or computer, as long as it has internet access. Its layout is responsive, that is, it adjusts according to the screen size of the equipment. The elderly registration modules were designed to allow the exchange of information about the elderly not only medical, but also including food preferences, habits that are important for daily well-being and exchange of personal photos between family and elderly. The caregivers module allows the exchange of information between caregivers' shifts, with information relevant to the care of the elderly, and the medical module allows access to health information relevant to the monitoring of the elderly. The application worked well and can represent an easy and safe way to improve the quality of life of individuals who depend on third parties for their care.
Avaliação da efetividade da genotipagem na triagem da infecção pelo Papilomavírus Humano (HPV) – Análise de resultados
(Universidade Brasil, 2023) Freitas, Giulia Pinheiro de; Zonta, Marco Antonio; Nunez, Silvia Cristina
Cervical cancer is a serious public health problem and is directly associated with human papillomavirus (HPV) infection. HPV is the most common sexually transmitted infection worldwide and has a high potential to evolve into malignancy, when arising from persistent and recurrent infections by types of high oncogenic potential. The main objective of this study is to evaluate a primary screening model for HPV infection based on the detection of viral DNA through the molecular microarray technique and to evaluate the main genotypes expressed, in order to establish a well-defined relationship between the incidence of high- oncotic potential with the presence of cytological alterations. This is a retrospective observational study analyzing the database of the Inside Diagnostics, Research and Development S.A laboratory, in São Paulo, in which the results of 1951 patients who underwent the HPV genotyping exam and oncotic cytology concomitantly, in the period from January to December 2022. The prevalence of HPV infection in the study population was 19.99%, with high-risk HPV infection being the most frequently found, present in 61.53% of cases. Genotype 16 (21.51%) was the most common among high-risk infections and type 54 (21.02%) the most common in low-risk HPV infections. HPV infections were more commonly observed in patients who presented lesions on cytology and the absence of infection by this virus was more common in patients with normal and inflammatory cytology. However, the presence of HPV was identified in 13.55% of cases with normal cytology. HPV genotyping is of paramount importance for the fight against cervical neoplasia, since this methodology makes it possible to assess the risk of developing precursor lesions and cervical cancer, anticipating the appearance of cervical lesions in up to ten years, therefore, it is essential to integrate this technique to cytological examinations. In addition, the identification of predominant genotypes in the precursor lesions that precede the oncogenic state allows drawing an epidemiological profile in order to increase the effectiveness of prevention and health promotion actions related to cervical cancer.
Avaliação do conhecimento sobre fotobiomodulação dos fisioterapeutas no Brasil
(Universidade Brasil, 2021) Arruda Neto, Euler; Nunez, Silvia Cristina
Physiotherapy is the profession that assesses, rehabilitates, prevents, recovers, as well as restores, develops, and conserves the individual's capacity through physical resources such as ultrasound, heat and light. Electrophysical resources are described and recommended in undergraduate courses and among these we find the use of low power lasers. Brazil is one of the countries with the most publications in the world in the area known as Photobiomodulation (PBM), however, it is not clear the access that physiotherapy clinicians have to the advances obtained in scientific research. The purpose of this study is to verify, through an electronic form, the knowledge of physical therapists enrolled in class councils about PBM in daily practice. An electronic questionnaire Google Form was developed, and it was sent by email, WhatsApp social networks, SMS, and printed forms were also distributed. The distribution started in the region of Goiás and the Federal District with the support of CREFITO 11 and then expanded to other regions. In total 106 physiotherapists answered the questionnaire. Of these 50% used lasers in the clinic, while 10.4% had never used lasers. After obtaining the data and according to the responses obtained, we observed 50% that physiotherapy professionals. 81.4% said they did not use it because they did not have the equipment and 10.2% indicated the cost as a reason for not using it. Among the participants, 62.3% said they had not made any updates in the area in the last 3 years and of those who said they had updated the courses up to 1 hour in duration were the majority. 76.5% also never calibrated their equipment and 45.7% said they used the protocols they learned at graduation. Based on the results, we conclude that there is a need for greater dissemination of the scientific knowledge obtained in the field of PBM in physical therapy so that the advances are effectively passed on to professionals who work clinically in the area.
Avaliação dos efeitos da fotobiomodulação sistêmica sobre os níveis de cortisol salivar
(Universidade Brasil) Trindade, Monaiza Moura; Navarro, Ricardo Scarparo; Magalhães, Daniel Souza Ferreira; Nunez, Silvia Cristina; Baptista, Alessandra
Dermatite induzida por produtos de higiene das mãos no contexto da pandemia de Covid-19
(Universidade Brasil, 2021) Almeida, Amanda Priscila; Nunez, Silvia Cristina; Navarro, Ricardo Scarparo
The COVID-19 pandemic ravaged the entire planet and important behaviors were reinforced by all health control agencies around the world, such as social distancing, the use of protective masks and hand hygiene, through washing with water and soap or application of alcohol gel. The aim of this study was to carry out an integrative review of the evidence in the literature on the characteristics of dermatitis induced by hand hygiene products in the context of the COVID-19 pandemic and to carry out a survey of information through a structured questionnaire on the behavior of the population and the hand hygiene care during 2020. An integrative review of articles was carried out, following the PICOS strategy, in Portuguese, English and Spanish, between December 2019 and April 2021, with the descriptors: contact dermatitis; hand dermatitis; hand disinfection; occupational dermatitis; occupational irritant hand dermatitis AND COVID-19; coronavirus; pandemic; pandemic; SARS-COV-2 with their corresponding terms in Portuguese and Spanish. The Boolean OR operator was applied between the terms. The search was performed in PubMed, MEDLINE, LILACS and Scielo databases. An electronic form was made available online to answer questions related to hand hygiene and cleaning habits within the context of the COVID-19 pandemic. According to the results, from the search for studies and with double and triple crossings, 557 articles were found, among these, 24 articles were selected related to the study topic. The answers to the questions were converted into numbers and the normality of the distribution of variables was tested using the Shapiro-Wilk test. The data obtained were analyzed by Student's t and Wilcoxon statistical tests and correlation analyzes were performed using the Pearson's Correlation Coefficient using the SPSS software (IBM SPSS Statistics for Windows, version 25.0.; IBM, Armonk, New York) in the interval 95% confidence. A total of 1027 responses to the questionnaire were obtained and it was observed that 21.4% of the participants had COVID-19 and 93% changed their hand hygiene habits after the pandemic, the habit of using alcohol gel was one of the biggest changes (83.1 %), 52.2% of the participants learned something new about cleaning their hands after the pandemic and 74.6% noticed a change in the skin on their hands after the onset of the pandemic. Among those interviewed, 8% had to seek medical help for problems with the skin on their hands. We can conclude that education measures on hand hygiene habits should persist as important public health actions and the quality of products used for hand hygiene should be a factor to be considered both by establishments that provide hygiene products and by purchased products by the users.
Dor femoropatelar: desequilíbrio e sobrecarga
(Universidade Brasil, 2020) Albuquerque, Carlos Eduardo de; Nunez, Silvia Cristina
Patellofemoral pain (PFP) is a multifactorial pathology difficulty to diagnose. Predominant in women at productive phase, PFP reduces physical performance, affects quality of life and psychosocial health of individuals with this condition. PFP has an insidious onset and remains delicately disturbing at all times in the individual. This paper aims to identify factors associated with PFP in women; and demonstrate the action of overload on the control of knee joint movement in the presence of PFD. To develop the proposal of this study are presented 3 articles and 1 mobile application. The articles discuss the lateral stabilization of the patella, performed by the iliotibial tract and the change in muscle activity caused by overload. The iliotibial tract is more than 60% thickened in the PFD group. Mechanical overload on the knee joint with PFD changed the relationship of muscular balance in the frontal plane of movement (between the vastus lateralis and medialis muscles) with increased activation of the vastus lateralis muscle. The mobile aplication to aid on PFP diagnosis provided an overview of the biopsychosocial status of the individual assessed according to function, quality of life, kinesiophobia and physical activity index questionnaire. PFP presents itself as a complex condition, compromising several systems and with poor diagnosis. This work contributed to the construction of tools to assist the diagnosis of PFP.
Efeito antibacteriano do óleo de girassol ozonizado em diferentes concentrações
(Universidade Brasil, 2021) Ficher, Ester; Nunez, Silvia Cristina
The world is currently facing a crisis regarding microorganisms and microbial resistance. The evaluation of alternative antimicrobial therapies has been a constant search in recent decades. Ozonized oil can be an alternative within this field. The present study aims to analyze the antimicrobial efficacy of commercially available ozonated sunflower oil in different concentrations. A gram-positive bacteria Staphylococcus aureus and the gram-negative bacteria Escherichia coli were used. The microorganisms were grown in BHI broth (Brain and Heart Infusion) for 24h. Plates containing BHI agar were prepared for the inhibition halo test with a 3 mm diameter central well and contaminated with 50 µL of bacterial suspension. The wells made in the plates were filled with ozonated sunflower oil in concentrations ranging from 80 mmol-Eq / kg to 1290 mmol-Eq /. The plates were taken to the incubator at 37°C for 24h and the inhibition zone was measured with a millimeter probe, two control groups one with non-ozonated sunflower oil and one with 2% chlorhexidine gluconate solution were also evaluated. The results demonstrated that the efficacy for E.coli increases linearly with increasing concentration, however, only the concentrations of 702 mmol-Eq / kg and 1290 mmol-Eq / kg were significantly different (p<0.004). For S.aureus, the results showed significant differences only in the concentration of 1290 mmol-Eq / kg, but with a similar effect between the intermediate and higher concentrations (p<0.0001). The chlorhexidine group demonstrated to have a more effective action for both microorganisms under the conditions of this study (p<0.001). According to the results ozonized sunflower oil has less antimicrobial effect than chlorhexidine, the result is dependent on the concentration and only concentrations above 702 mmol-Eq / kg showed some efficacy.
Ensaio clínico cego e randomizado para avaliação de dois protocolos de Fotobiomodulação para a prevenção das complicações orais em pacientes transplantados de medula óssea
(Universidade Brasil, 2021) Marski, Roberta Silveira da Silva; Nunez, Silvia Cristina
Bone marrow transplantation (BMT) or hematopoietic cell transplantation requires high doses of chemotherapy in patients who will undergo HSCT (Hematopoietic Stem Cell Transplantation), this chemotherapy regimen causes the destruction of cells with a high mitotic index leading to damage to the oral and gastric mucosa called Mucositis. The aim of this study was to investigate the efficacy of Photobiomodulation (PBM) in the prevention of oral complications in hematopoietic transplant patients applying PBM daily and comparing it to the application every other day, totalizing 4 weekly applications from the beginning of conditioning to neutrophilic engraftment (bone marrow engraftment) in gender-independent, halogen and/or haploidentical transplant recipients. The volunteers were randomly divided into 2 groups: Daily Laser Group (DLG) P=13; LG4 (4x a week) P=17. All groups were evaluated daily by a trained nursing staff., from the beginning of conditioning D-7 to D+21, the results were cataloged and analyzed in a blind, longitudinal study, according to the WHO scale for evaluation of oral mucositis and pain degree (VAS scale). The groups were submitted to low power laser treatment (Therapy XT-DMC, São Carlos, Brazil) with a wavelength of 660nm, Power of 100mW, exposure time of 20 s delivering 2J per point throughout the oral cavity. Data related to xerostomia, odynophagia and degree of mucositis were analyzed over 21 days and the data were compared statistically using the Mann-Whitney test. The statistical comparison results for xerostomia (D+8 p=0.4434), odynophagia (D+8 p=0.8560) and mucositis (D+8 p=0.7285) showed no significant differences at any time during the study. According to the results, the PBM protocol on alternate days is as efficient as the daily application for the prevention of oral complications in patients who underwent HSCT.
Ensaio clínico sobre o efeito da Fotobiomodulação e da Terapia Fotodinâmica na cicatrização de lesões crônicas
(Universidade Brasil, 2021) Moreira, Isabel Cristina Cavalcante Carvalho; Nunez, Silvia Cristina
Introduction: Chronic wounds can be defined as those that do not advance in relation to the orderly tissue repair process and compromise anatomical integrity and tissue repair time. Neuropathic ulcers are chronic lesions and one of the most stigmatizing sequelae of diabetic foot and leprosy-associated wounds, their presence is quite impairing for the individual and can lead to deformation and/or amputation of the affected limb. For the treatment of these wounds, there are a variety of existing topical products, including hydrogel. Besides, treatment through the use of photobiomodulation therapy (PBM) and photodynamic therapy (PDT) has shown positive results in the repair process. Objective: To evaluate the effects of PBM and PDT with methylene blue, associated or not with urea, on the healing of chronic wounds caused by diabetes and leprosy. Methodology: This is a blind randomized clinical trial. There were 17 volunteers with chronic diabetes wounds that were divided into 4 groups: Group I hydrogel with alginate (n=3), Group II PBM with diode laser λ= 660 nm, power of 100 mW, with 4J applied every 1 cm (n=6), Group III PDT with methylene blue at 100 µM associated with red emission diode laser λ = 660 nm, power of 100 mW with 9 J every 1 cm (n=5), and Group IV methylene blue 100 µM PDT associated with 2M urea (n=4) and the same irradiation parameters as G III. And 13 volunteers with chronic leprosy lesions divided into 4 groups: Group I hydrogel with alginate (n=3); Group II PBM with diode laser λ= 660 nm, power of 100 mW, with 4J applied every 1 cm (n=4) ; Group III PDT with methylene blue at 100 µM associated with red emission diode laser λ = 660 nm, power of 100 mW with 9 J every 1 cm (n=3) and Group IV PDT with methylene blue at 100 µM associated with 2M urea and the same irradiation parameters as G III. For the intervention protocol, the volunteers underwent 8 sessions, comprising 2 sessions a week, on alternate days. Photographic records were used for the macroscopic evaluation throughout the sessions and the measurement of the wound was related to the greatest length versus the greatest width. For all groups, the Pressure Ulcer Scale for Healing (PUSH), was applied to assess the healing process. Results: This study found that diabetic individuals undergoing hydrogel therapy (G I) did not present a reduction in chronic wound size. As measured by the PUSH score, it was not statistically significant (p value = 0.317). However, it was observed that there was a significant reduction in the size of the 9 chronic lesion measured by the PUSH Score between days 1 and 8 in individuals with diabetes for groups G II (p<0.001), G III (p=0.004) and G IV (p=0.001). It was found that in individuals with leprosy undergoing hydrogel therapy, the reduction of chronic wound, measured by the PUSH score, was not statistically significant (p value = 0.096). However, it was observed that there was a significant reduction in the size of the chronic lesion measured by the PUSH score between days 1 and 5 in individuals with leprosy for G II (p value = 0.021), G III (p value = 0.005 ) and G IV PDT+AM 100 µM associated with 2M urea (p value = 0.034). Conclusion: The therapies with PBM and PDT with methylene blue, and PDT with methylene blue associated with urea reduce the size of the chronic wound in diabetic patients, requiring 3 applications. All light therapies evaluated in the study reduced the size of chronic wounds in leprosy patients after five applications.
Fotobiomodulação como ferramenta auxiliar na hidratação cutânea
(Universidade Brasil, 2023) Foguel, Cicelina Campos; Nunez, Silvia Cristina
Cutaneous dehydration is one of the changes caused by aging that has a high frequency. Although not considered a dysfunction in itself, xerosis can cause discomfort due to the visual and sensory appearance of the skin. The use of photonic techniques such as photobiomodulation (PBM) using LASER or LED has shown numerous benefits for skin healingr. The present study verified the ability of FBM to improve skin hydration associated with a cosmetic treatment protocol for cutaneous xerosis. The experimental model consisted of 3 sessions of cutaneous hydration performed in 60 volunteers, randomly divided into 2 groups, being the Experimental group where the hydration protocol will be associated with the application of red LED (660 nm, 3 J punctual application on the entire face) in each session of treatment and the control group that received the same hydration protocol and placebo LED irradiation. The results were evaluated by cutaneous bioimpedance on the first day and one week after the last day of treatment, and the appearance of the skin was evaluated by evaluators blinded to the treatment protocol used. The data obtained were statistically compared. We observed with this study that there is a role for the use of PBM in the process of reversal of cutaneous xerosis, we identified an improvement in the amount of water in the skin without changing the amount of oil. PBM can be used in the treatment of patients who show signs of skin dehydration, senile xerosis, who are looking for a safe, non-invasive technique with no side effects, as well as patients who have contraindications to the use of other therapies available in the aesthetic market. Emphasizing that it is a very useful tool for hydration of oily biotype skins, since it increased the water gradient and there was no change in the percentage of oil.
Fotobiomodulação no manejo da mucosite oral em hospitais do Brasil: a busca por uma diretriz clínica
(Universidade Brasil, 2022) Passos, Januaria Lima Ribeiro; Nunez, Silvia Cristina
Cancer is one of the most frequent diseases worldwide. Oral mucositis (OM) is a common and debilitating complication of chemotherapy (CT), head and neck radiotherapy (RT) and hematopoietic stem cell transplantation (HSCT). Photobiomodulation (PBM) IS one of the therapeutic alternatives for prevention and treatment of OM. The objective of this study was to carry out a survey of data from the protocols applied for PBM in public and private hospitals in Brazil. A cross-sectional, quantitative study was carried out with the application of questionnaires to dentists, built specifically to understand the establishment of protocols and their outcomes, to verify if there is a consensus on the use of PBM in OM in Brazil. According to the analysis of the results, we observed that dentists work both in public and private hospitals in Brazil and most of them are employed by the institution. The PBM protocols, as well as, the initial assessment of patients, are performed by the dental surgeon who claims to use protocols based on scientific evidence. More modern equipment’s with 100 mW of power are the most used ones and, according to the interviewees, frequently checked. For OM induced by QT and HSCT, preventive and therapeutic protocols were cited, while for RT only one protocol was cited. The prevailing wavelength was red, and only for therapeutic HSCT the 2 wavelengths had the same frequencies. In all cases, energies of 1 and 2 J were the prevailing ones, with irradiation performed in a punctual way. The frequency of irradiation depends on the duration of RT, or it is performed for 5 days in a week for QT and HSCT, and only in therapeutic HSCT did the interviewees point out the symptomatology and the clinical aspect as relevant for the choice of treatment. According to our results, the treatment of OM with PBM presents constancy of energy and form of application, which may explain its spread and successful application in different regions of the country in a homogeneous way.