Navegando por Autor "Nuñez, Silvia Cristina"

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Aplicativo móvel multiplataforma para gestão de cuidados de idosos
(Universidade Brasil, 2021) Chagas, Renata Kelen; Nuñez, Silvia Cristina
The aging of the world population has been taking place in recent decades as result of the decrease in birth rates and better health care that allows for an increase in life expectancy. Senile dementias are examples of diseases that can affect the elderly, reducing independence and self-care. With the presence of women in the labor market and the reduced number of children, the elderly must often live under the care of others who have professional experience to provide appropriate medical care, but lack of contact with the family and unfamiliarity with habits and tastes can reduce the quality of life of the elderly. Technological advances must be used to reduce the distance between families, caregivers, doctors and the elderly. The objective of this work is to develop an application for mobile devices that facilitates communication between health service providers for the elderly residing in long-stay institutions. The CuidaLife application was developed for a software operating system with input modules for registering elderly people, family members, doctors and caregivers. The developed application can be accessed through any smartphone, tablet or computer, as long as it has internet access. Its layout is responsive, that is, it adjusts according to the screen size of the equipment. The elderly registration modules were designed to allow the exchange of information about the elderly not only medical, but also including food preferences, habits that are important for daily well-being and exchange of personal photos between family and elderly. The caregivers module allows the exchange of information between caregivers' shifts, with information relevant to the care of the elderly, and the medical module allows access to health information relevant to the monitoring of the elderly. The application worked well and can represent an easy and safe way to improve the quality of life of individuals who depend on third parties for their care.
Avaliação do conhecimento sobre fotobiomodulação dos fisioterapeutas no Brasil
(Universidade Brasil, 2021) Arruda Neto, Euler; Nuñez, Silvia Cristina
Physiotherapy is the profession that assesses, rehabilitates, prevents, recovers, as well as restores, develops, and conserves the individual's capacity through physical resources such as ultrasound, heat and light. Electrophysical resources are described and recommended in undergraduate courses and among these we find the use of low power lasers. Brazil is one of the countries with the most publications in the world in the area known as Photobiomodulation (PBM), however, it is not clear the access that physiotherapy clinicians have to the advances obtained in scientific research. The purpose of this study is to verify, through an electronic form, the knowledge of physical therapists enrolled in class councils about PBM in daily practice. An electronic questionnaire Google Form was developed, and it was sent by email, WhatsApp social networks, SMS, and printed forms were also distributed. The distribution started in the region of Goiás and the Federal District with the support of CREFITO 11 and then expanded to other regions. In total 106 physiotherapists answered the questionnaire. Of these 50% used lasers in the clinic, while 10.4% had never used lasers. After obtaining the data and according to the responses obtained, we observed 50% that physiotherapy professionals. 81.4% said they did not use it because they did not have the equipment and 10.2% indicated the cost as a reason for not using it. Among the participants, 62.3% said they had not made any updates in the area in the last 3 years and of those who said they had updated the courses up to 1 hour in duration were the majority. 76.5% also never calibrated their equipment and 45.7% said they used the protocols they learned at graduation. Based on the results, we conclude that there is a need for greater dissemination of the scientific knowledge obtained in the field of PBM in physical therapy so that the advances are effectively passed on to professionals who work clinically in the area.
Avaliação microbiológica da associação do biopolímero de fibrina com nitrato de prata
(Universidade Brasil, 2021) Campos, Silvana; Nuñez, Silvia Cristina; Cogo, José Carlos
Fibrin sealants, also known as fibrin biopolymer (BPF), are biological matrixes from human plasma, fully resorbable, that mimic the last stages of the coagulation cascade during which fibrinogen is converted into a structured and insoluble fibrin clot. BPF developed from the snake venom Crotalus durissus terrificus, presents an excellent alternative for tissue engineering and cell modulation. Its use as a healer for venous ulcers in the lower limbs proved to be safe and potentially effective in a phase II clinical study. Objective: To investigate the antimicrobial effect of the association of fibrin biopolymer with silver nitrate. This association will allow its use in contaminated and colonized wounds, which currently leads to suspension of treatment with BPF. Methods: BPF is prepared from 2 active components and a diluent. Different concentrations of silver nitrate were mixed with the BPF components. The clots containing silver nitrate were inserted into the wells drilled on the agar in Petri dishes containing the culture medium of Mueller Hilton agar previously seeded with cultures of Staphylococcus aureus and Escherichia coli. Silver nitrate concentrations were used, forming the following groups: Control - NP1 = 1mg / mL; NP2 = 2.5mg / mL and NP3 = 5mg / mL silver nitrate; Experimental group: the same concentrations used in the control group associated with BPF and positive control with antibiotics. The presence was verified and the inhibition halo present in each of the tested plates was measured. Tests of minimum inhibitory concentration (CIM) and minimum bactericide (CBM) were carried out to establish the lowest concentration of BPF + NP and NP capable of inhibiting the tested strains. Mean and median values of diameters with measures of central tendency and standard deviation and interquartile range were considered as measures of sample dispersion and verification of antimicrobial efficacy. Results: A significant difference was observed in the halos of inhibition of treatments with NP when compared with BPF + NP. There was a statistical difference in the inhibition halos of the gram-negative bacteria in relation to the gram-positive bacteria, in the treatment with NP, NP3 showed a significant difference in relation to NP2 compared to E. coli while S. aureus did not present a statistically significant difference. BPF alone did not form an inhibition halo. BPF + NP had an inhibitory effect on the antimicrobial action of NP by 18.2% for E. coli and 13.5% for S. aureus when compared to NP treatment. The CIM found for E. coli and S. aureus when tested with GMP + NP were 7.81 and 250 µg / mL and with NP 3.9 and 7.81 µg / mL. While CBM found for BPF + NP they were 15.62 and 1000 µg / mL and for treatment with NP 7.81 and 15.62 µg / mL respectively. Conclusion: It was possible to verify by the results that the NP and BPF + NP showed antibacterial effect on the species of gram-negative and grampositive bacteria, demonstrating greater efficacy for E. coli and that the antibacterial activity of the NP was more effective than the BPF + NP. He observed that GMP when isolated has no antibacterial effect.
Dermatite induzida por produtos de higiene das mãos no contexto da pandemia de Covid-19
(Universidade Brasil, 2021) Almeida, Amanda Priscila; Navarro, Ricardo Scarparo; Nuñez, Silvia Cristina
The COVID-19 pandemic ravaged the entire planet and important behaviors were reinforced by all health control agencies around the world, such as social distancing, the use of protective masks and hand hygiene, through washing with water and soap or application of alcohol gel. The aim of this study was to carry out an integrative review of the evidence in the literature on the characteristics of dermatitis induced by hand hygiene products in the context of the COVID-19 pandemic and to carry out a survey of information through a structured questionnaire on the behavior of the population and the hand hygiene care during 2020. An integrative review of articles was carried out, following the PICOS strategy, in Portuguese, English and Spanish, between December 2019 and April 2021, with the descriptors: contact dermatitis; hand dermatitis; hand disinfection; occupational dermatitis; occupational irritant hand dermatitis AND COVID-19; coronavirus; pandemic; pandemic; SARS-COV-2 with their corresponding terms in Portuguese and Spanish. The Boolean OR operator was applied between the terms. The search was performed in PubMed, MEDLINE, LILACS and Scielo databases. An electronic form was made available online to answer questions related to hand hygiene and cleaning habits within the context of the COVID-19 pandemic. According to the results, from the search for studies and with double and triple crossings, 557 articles were found, among these, 24 articles were selected related to the study topic. The answers to the questions were converted into numbers and the normality of the distribution of variables was tested using the Shapiro-Wilk test. The data obtained were analyzed by Student's t and Wilcoxon statistical tests and correlation analyzes were performed using the Pearson's Correlation Coefficient using the SPSS software (IBM SPSS Statistics for Windows, version 25.0.; IBM, Armonk, New York) in the interval 95% confidence. A total of 1027 responses to the questionnaire were obtained and it was observed that 21.4% of the participants had COVID-19 and 93% changed their hand hygiene habits after the pandemic, the habit of using alcohol gel was one of the biggest changes (83.1 %), 52.2% of the participants learned something new about cleaning their hands after the pandemic and 74.6% noticed a change in the skin on their hands after the onset of the pandemic. Among those interviewed, 8% had to seek medical help for problems with the skin on their hands. We can conclude that education measures on hand hygiene habits should persist as important public health actions and the quality of products used for hand hygiene should be a factor to be considered both by establishments that provide hygiene products and by purchased products by the users.
Efeito antibacteriano do óleo de girassol ozonizado em diferentes concentrações
(Universidade Brasil, 2021) Ficher, Ester; Nuñez, Silvia Cristina
The world is currently facing a crisis regarding microorganisms and microbial resistance. The evaluation of alternative antimicrobial therapies has been a constant search in recent decades. Ozonized oil can be an alternative within this field. The present study aims to analyze the antimicrobial efficacy of commercially available ozonated sunflower oil in different concentrations. A gram-positive bacteria Staphylococcus aureus and the gram-negative bacteria Escherichia coli were used. The microorganisms were grown in BHI broth (Brain and Heart Infusion) for 24h. Plates containing BHI agar were prepared for the inhibition halo test with a 3 mm diameter central well and contaminated with 50 µL of bacterial suspension. The wells made in the plates were filled with ozonated sunflower oil in concentrations ranging from 80 mmol-Eq / kg to 1290 mmol-Eq /. The plates were taken to the incubator at 37°C for 24h and the inhibition zone was measured with a millimeter probe, two control groups one with non-ozonated sunflower oil and one with 2% chlorhexidine gluconate solution were also evaluated. The results demonstrated that the efficacy for E.coli increases linearly with increasing concentration, however, only the concentrations of 702 mmol-Eq / kg and 1290 mmol-Eq / kg were significantly different (p<0.004). For S.aureus, the results showed significant differences only in the concentration of 1290 mmol-Eq / kg, but with a similar effect between the intermediate and higher concentrations (p<0.0001). The chlorhexidine group demonstrated to have a more effective action for both microorganisms under the conditions of this study (p<0.001). According to the results ozonized sunflower oil has less antimicrobial effect than chlorhexidine, the result is dependent on the concentration and only concentrations above 702 mmol-Eq / kg showed some efficacy.
Ensaio clínico cego e randomizado para avaliação de dois protocolos de fotobiomodulação para a prevenção das complicações orais em pacientes transplantados de medula óssea
(Universidade Brasil, 2021) Marski, Roberta Silveira da Silva; Nuñez, Silvia Cristina
Bone marrow transplantation (BMT) or hematopoietic cell transplantation requires high doses of chemotherapy in patients who will undergo HSCT (Hematopoietic Stem Cell Transplantation), this chemotherapy regimen causes the destruction of cells with a high mitotic index leading to damage to the oral and gastric mucosa called Mucositis. The aim of this study was to investigate the efficacy of Photobiomodulation (PBM) in the prevention of oral complications in hematopoietic transplant patients applying PBM daily and comparing it to the application every other day, totalizing 4 weekly applications from the beginning of conditioning to neutrophilic engraftment (bone marrow engraftment) in gender-independent, halogen and/or haploidentical transplant recipients. The volunteers were randomly divided into 2 groups: Daily Laser Group (DLG) P=13; LG4 (4x a week) P=17. All groups were evaluated daily by a trained nursing staff., from the beginning of conditioning D-7 to D+21, the results were cataloged and analyzed in a blind, longitudinal study, according to the WHO scale for evaluation of oral mucositis and pain degree (VAS scale). The groups were submitted to low power laser treatment (Therapy XT-DMC, São Carlos, Brazil) with a wavelength of 660nm, Power of 100mW, exposure time of 20 s delivering 2J per point throughout the oral cavity. Data related to xerostomia, odynophagia and degree of mucositis were analyzed over 21 days and the data were compared statistically using the Mann-Whitney test. The statistical comparison results for xerostomia (D+8 p=0.4434), odynophagia (D+8 p=0.8560) and mucositis (D+8 p=0.7285) showed no significant differences at any time during the study. According to the results, the PBM protocol on alternate days is as efficient as the daily application for the prevention of oral complications in patients who underwent HSCT.
Estudo clínico cego e randomizado sobre o efeito da fotobiomodulação e da terapia fotodinâmica na cicatrização de lesões crônicas
(Universidade Brasil, 2021) Moreira, Isabel Cristina Cavalcante Carvalho; Nuñez, Silvia Cristina
Chronic wounds can be defined as those that do not advance in relation to the orderly tissue repair process and compromise anatomical integrity and tissue repair time. Neuropathic ulcers are chronic lesions and one of the most stigmatizing sequelae of diabetic foot and leprosy-associated wounds, their presence is quite impairing for the individual and can lead to deformation and/or amputation of the affected limb. For the treatment of these wounds, there are a variety of existing topical products, including hydrogel. Besides, treatment through the use of photobiomodulation therapy (PBM) and photodynamic therapy (PDT) has shown positive results in the repair process. Objective: To evaluate the effects of PBM and PDT with methylene blue, associated or not with urea, on the healing of chronic wounds caused by diabetes and leprosy. Methodology: This is a blind randomized clinical trial. There were 17 volunteers with chronic diabetes wounds that were divided into 4 groups: Group I hydrogel with alginate (n=3), Group II PBM with diode laser λ= 660 nm, power of 100 mW, with 4J applied every 1 cm (n=6), Group III PDT with methylene blue at 100 µM associated with red emission diode laser λ = 660 nm, power of 100 mW with 9 J every 1 cm (n=5), and Group IV methylene blue 100 µM PDT associated with 2M urea (n=4) and the same irradiation parameters as G III. And 13 volunteers with chronic leprosy lesions divided into 4 groups: Group I hydrogel with alginate (n=3); Group II PBM with diode laser λ= 660 nm, power of 100 mW, with 4J applied every 1 cm (n=4) ; Group III PDT with methylene blue at 100 µM associated with red emission diode laser λ = 660 nm, power of 100 mW with 9 J every 1 cm (n=3) and Group IV PDT with methylene blue at 100 µM associated with 2M urea and the same irradiation parameters as G III. For the intervention protocol, the volunteers underwent 8 sessions, comprising 2 sessions a week, on alternate days. Photographic records were used for the macroscopic evaluation throughout the sessions and the measurement of the wound was related to the greatest length versus the greatest width. For all groups, the Pressure Ulcer Scale for Healing (PUSH), was applied to assess the healing process. Results: This study found that diabetic individuals undergoing hydrogel therapy (G I) did not present a reduction in chronic wound size. As measured by the PUSH score, it was not statistically significant (p value = 0.317). However, it was observed that there was a significant reduction in the size of the 9 chronic lesion measured by the PUSH Score between days 1 and 8 in individuals with diabetes for groups G II (p<0.001), G III (p=0.004) and G IV (p=0.001). It was found that in individuals with leprosy undergoing hydrogel therapy, the reduction of chronic wound, measured by the PUSH score, was not statistically significant (p value = 0.096). However, it was observed that there was a significant reduction in the size of the chronic lesion measured by the PUSH score between days 1 and 5 in individuals with leprosy for G II (p value = 0.021), G III (p value = 0.005 ) and G IV PDT+AM 100 µM associated with 2M urea (p value = 0.034). Conclusion: The therapies with PBM and PDT with methylene blue, and PDT with methylene blue associated with urea reduce the size of the chronic wound in diabetic patients, requiring 3 applications. All light therapies evaluated in the study reduced the size of chronic wounds in leprosy patients after five applications.