Avaliação da fototerapia com diferentes comprimentos de onda no tratamento da Alopécia androgenética

Abstract

Androgenetic alopecia (AGA) is a hair dysfunction that promotes the transformation of terminal hairs into vellus hairs and consequent baldness. Phototherapy (FT) uses light, usually laser or LED, to stimulate, heal and/or regenerate damaged tissues and has been identified as a safe and promising resource for the treatment of AGA. The purpose of this study is to compare different wavelengths in the treatment of AGA. 10 volunteers were selected, randomly divided into 2 groups: Red Light Group (GLV, n=5) and Blue Light Group (GLA, n=5). The groups received point irradiation (4J/point), respectively, with the Venus equipment (MMOptics, São Carlos, Brazil), GLV (l= 660nm, P= 100 mW, for 40 s) and GLA (l= 440 nm, P = 150 mW, for 26.6 s). The interventions were carried out once a week, for 90 days, totaling 12 treatment sessions. The emergence of new hairs was analyzed by comparing the photographic record before any intervention (T1) and at the end of treatment (T2). The relationship between vellus threads and terminal threads was analyzed by trichoscopy with polarized light, before and at the end of treatment. A specific quality of life assessment questionnaire for androgenetic alopecia (Women's Androgenetic Alopecia Quality of Life Questionnaire -WAA-QoL) before and after the end of the interventions. The results showed that both red light and blue light, in the parameters tested in this study, led to an increase in the number of terminal strands after treatment (p< 0.05), which allowed a reduction in the central parting of the treated hair. The evaluation of the WAA-QoL questionnaire showed a lower percentage of responses with a higher degree of dissatisfaction after both treatments. Therefore, we can conclude that the use of phototherapy is an effective therapeutic resource in the treatment of AGA with red or blue light, in the parameters tested in this study.