Monografias, Dissertações e Teses
URI permanente desta comunidadehttps://repositorioacademico.universidadebrasil.edu.br/handle/123456789/1
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Item Terapia de fotobiomodulação controla a glicemia em pessoas com diabetes do tipo 2?: uma revisão sistemática e metanálise(Universidade Brasil, 2022) Silva, Nélida Amorim da Silva; Parizotto, Nivaldo Antonio; Ferraresi, Cleber (Coorientador)Reducing high glycemic levels is essential for the health of people with type 2 diabetes mellitus (DM2). Drug treatments have adverse side effects, and they lose their effectiveness over the years, in addition to being expensive and sometimes invasive. Photobiomodulation Therapy (TFBM) appears as a new alternative in the treatment of people with DM2, since it has shown positive effects on glycemic control in animals and humans, when associated with another therapy. Objective: To analyze the effects of TFBM on glycemic control in people with DM2. Method: Systematic review with meta-analysis of randomized clinical trials (RCTs) present in PUBMED, EMBASE, CENTRAL and Web of Science databases. Participants: People with DM2. Intervention: TFBM alone compared to control or placebo, or TFBM as an adjunct to another intervention. Outcome: Blood glucose reduction through blood tests performed before and after the intervention. Result: From n=329 studies, 10 were included. We found 1 RCT that compared TFBM alone versus a control group. In 8 RCTs, TFBM was added to another intervention in people with periodontitis and T2DM. In 1 RCT, TFBM was added to aerobic exercise. The meta-analysis of 4 RCTs with similar methodologies showed that TFBM added to scaling was significantly superior in reducing blood glucose when compared to control in people with periodontitis and T2DM. The overall quality of the GRADE evidence gave a low level of certainty. Conclusion: Due to the scarcity of studies, there is currently no evidence linking TFBM alone and the reduction of blood glucose in people with DM2. The present systematic review corroborates the existing evidence that supports the additional use of TFBM combined with conventional scaling, as an aid in glycemic control in the treatment of people affected with periodontitis and T2DM. PROSPERO CRD42021238280.Item A relação entre a irradiação transcutânea do sangue – ILIB modificada e os níveis de cortisol salivar em cuidadores de idosos saudáveis(Universidade Brasil, 2021) Trindade, Monaiza Moura; Baptista, AlessandraFormal caregivers usually have exhaustive work scale that can trigger emotional changes and a decrease in the quality of life of these professionals. The use of ILIB (Intravascular Laser Irradiation of Blood) can improve the immunological activity of the blood, in addition to facilitating blood circulation and has been used in the treatment of different diseases. The aim of this study was to verify the effects of ILIB, applied transcutaneous, in relation to the levels of salivary cortisol of caregivers of formal elderly in long-term care institutions, who work during the day and night. Forty-two caregivers of formal elderly people were divided into 6 groups: Day Group (DG) (n=7); Day ILIB Group (DILIBG) (n=7); Day ILIB/placebo group (DPG) (n=7); Night Group (NG) (n=7); ILIB Night Group (NILIBG) (n=7); and Night ILIB/placebo Group (NPG) (n=7). Volunteers in the ILIB and ILIB / placebo groups received ILIB, in the radial artery region, by means of a low-power laser (Laser Duo, MMOPTICS, São Carlos, Brazil), l= 660 nm, P = 100 mW / 30 min, every other day, for 2 weeks, totaling 8 sessions of treatment/placebo, while the groups: GD and GN performed salivary collection on the day off and on the workday. All participants answered the quality of life questionnaire (QLQ) before any procedure and saliva collections for volunteers in the ILIB and ILIB/placebo groups were performed before any procedure; 24 h and 48 h after 8 treatment/placebo sessions, while the groups: DN and NG performed salivary collection on the day off and on the workday. The QLQ results did not show statistically significant differences between daytime and nighttime workers (p>0.05). Regarding cortisol quantification, the results showed statistically significant decreases (p<0.05) in salivary cortisol levels, both in the ILIB groups and in the placebo groups. Therefore, we can conclude that it was possible to measure the salivary cortisol levels of caregivers of formal elderly in long-stay institutions, who work day and night, treated or not with ILIB. However, ILIB cannot help to reduce salivary cortisol levels in caregivers of elderly people in long-term care facilities.