
Repositório Acadêmico UB
O Repositório Acadêmico da Universidade Brasil é uma plataforma digital de acesso aberto, cujo propósito central é a indexação, o armazenamento, a disseminação e o incentivo à produção de conhecimento gerado pela comunidade acadêmica, concentrando-o em um único ambiente virtual, com vistas à preservação da memória institucional e da identidade intelectual da Universidade.
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Submissões Recentes
A separação dos Poderes no Brasil: estrutura, funcionamento e participação cidadã: a implementação da disciplina de Direito Constitucional no Ensino Médio
(Universidade Brasil, 2025) Prada, Caroline Padovezi; Feitoza, Liliam Alvez
Universidade Brasil é nota máxima no curso de Direito
(Universidade Brasil, 2025) CRISPIM, Jornalista; .
An assessment carried out by the Ministry of Education at the Fernandópolis campus recognizes the institution's quality and academic excellence.
Unicastelo e Descalvado: a parceria que deu certo
(Universidade Camilo Castelo Branco, 2000) Junqueira, José Luiz Cintra; .
Síntese, determinação estrutural, análise dos orbitais naturais de ligação e estudo espectroscópico vibracional e eletrônico do composto de coordenação BIS (Dietilditiocarbamato) Ferro(II) [Fe(DDTC)2].
(Universidade Brasil, 2023) Télles Zepeda, Claudio Andrés; Pessoa, Rodrigo Sávio
We performed the synthesis, computational molecular modeling and vibrational/electronic spectroscopic analysis of the coordination complex Iron(II) Bis(Diethyldithiocarbamate) [Fe(DDTC)2]. The optimization of the molecular structure was performed using Density Functional Theory with the functional B3LYP and basis set 6-311G(d,p). The experimental FT-IR and Raman spectra of the complex were recorded in the range 4000 – 0 cm-1, in order to correlate them with the calculated spectra. Most of the DFT calculated frequencies were found to agree with the experimental results. In order to investigate the internal electronic mobility of the complex, we performed the natural bond orbital analysis (NBO), which provides information regarding intramolecular charge transfer interactions that result from the overlapping of bonding and antibonding orbitals, as well as information about the electronic distribution between the HOMO and LUMO orbitals due to charge transfers. We also correlated the calculated and experimental UV-Vis spectra in order to investigate the configurations of several excited states of the complex that involve intra-ligand transitions. The results corroborate the existence of several Ligand to Metal and and Metal to Ligand charge transfer transitions, as well as metal-centered d-d transitions.
Uso da Ozonioterapia em fungos causadores de Onicomicoses: estudo in vitro
(Universidade Brasil, 2024) Del Castilo, Denise Vivianni Ferreira; Assis, Lívia; Tim, Carla Roberta
: Onychomycosis is a common fungal infection of the nails, predominantly caused by dermatophytes such as Trichophyton rubrum (T. rubrum) and Microsporum gypseum (M. gypseum) and is a notoriously difficult condition to treat. Thus, the objective of the present study was to evaluate and compare, in vitro, the effectiveness of different times of ozone therapy on the main fungi that cause onychomycosis. Dermatophyte fungi T. rubrum (ATCC 28188) and M. gypseum (ATCC 24102) were incubated at 28° C for 14 days. Subsequently, the fungi were divided into 9 experimental groups according to the experimental time: Control Group (CG): the fungi were cultivated and did not receive any treatment; Cultivated fungi and received ozone therapy for a time of 2 min (G2”); 4 min (G4”); 6 min (G6”); 8 min (G8”); 10 min (G10”); 12 min (G12”); 14 min (G14”) and 16 min (G16”). The ozone concentration used was 2 µg/mL, oxygen flow of 1/4 L/min and applied dosages of 157, 314, 451, 628, 785, 943, 1100 and 1257 mg/m2, respectively. The main results show that the use of topical ozone therapy was effective in reducing the germination percentage of T. rubrum and M. gypseum in all experimental periods, presenting complete eradication with a treatment time of 6 min for T. rubrum and 14 min for M. gypseum. In conclusion, ozone therapy used topically, with emphasis on the treatment time of 6 min for T. rubrum (628 mg/m2) and 14 min (1257 mg/m2) for M. gypseum, promoted antifungal action on the main dermatophytes responsible for critical complications of onychomycosis, and may be proposed as a adjuvant in dermatological treatments.