2022-11-282022-11-282020https://repositorioacademico.universidadebrasil.edu.br/handle/123456789/326Some species of fungi are capable of causing mycotic infections. One of these infections is dermatophytosis, caused by a group of fungi, called dermatophytes. another infection is sporotrichosis, caused by species of Prothorax schenckii. The treatment of the disease is carried out using conventional antifungals. The emergence of resistant strains has led to alternative treatments, such as natural medicines or the use of ozone gas. The objective of this research was to evaluate the antifungal activity of fresh and ozonated essential oils against Trichophyton mentagrophytes, Trichophyton rubrum, and Sporothrix schenckii. In natura and ozonized essential oils of Cinnamomum cassia, Eugenia Caryphollata, Cymbopogon winterianus, Eucalyptus globulus, Eucalyptus staigeriana and Mentha piperita were used, evaluated for antifungal activity against the microorganism lineage. The oils were ozonized in corona equipment. The microdilution technique was used to assess the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC). The fungicidal kinetics of essential oils were determined. The data obtained were evaluated by the Mann-Whitney test and by the east of Kruskal-Wallis. The fungus T. mentagrophytes was more resistant. T. rubrum showed less resistance to treatments, showing decreases in microbial count in the first moments of exposure. The Spothrix fungus showed greater resistance to cinnamon, clove and Eucalyptus staigeriana oils, showing a decrease in microbial count variation. In general, the results show the possibility of use in antifungal therapy against the studied microorganisms.PDFpt-BRopenAccessTrichophyton mentagrophytesTrichophyton rubrumSporothrix schenckiiOzônioPlantas medicinaismasterThesisCB